Webpages of Dr. Ilya Reviakine

Brief CV

Research Interests

Education

Postdoctoral work

Independent work

Short stays

Committee and Organizational activities

Mentorship, supervision

Invited Talks

Research Interests

Platelets (thrombocytes), platelet activation and secretion, platelet-biomaterial interactions.

The role of platelets in blood-biomaterial interactions and hemocompatibility.

Interfaces between biological and artificial systems; biosurfaces, biointerfaces.

Lipid biophysics, cell membrane biophysics, aminophospholipid asymmetry, solid-supported lipid bilayers.

Surface and interface analysis: Atomic force microscopy (AFM) of biological systems in liquids; Quartz Crystal Microbalance (QCM); Secondary Ion Mass Spectrometry (SIMS) for solving biomedical problems; Neutron reflectometry; X-ray photoelectron spectroscopy.

Education

October 1996 - November 2000	Ph.D. in Mathematics and Natural Sciences from the University of Groningen, the Netherlands. Doctoral Thesis: Atomic Force Microscopy of Biological Macromolecules and Their Assemblies.
September 1992 - April 1996	B.Sc. (Honours) Biochemistry, Minor in Computer Sciences. McMaster University, Hamilton, Ontario, Canada.
October 1994 - June 1995	Exchange student at the University of Leeds (Leeds, UK).

Postdoctoral work

January 2005 – September 2006	Alexander von Humboldt Foundation Fellow at the Technical University of Clausthal, Clausthal-Zellerfeld, Germany. Host: Prof. Diethelm Johannsmann. Surface Acoustic Sesing
January 2002 – September 2004	Senior Research Associate, Department of Chemical Engineering, University of Houston (Houston, TX, USA). Protein Crystallization
October 2000 – January 2002	BioInterfaceGroup, Laboratory for Surface Science and Technology, Department of Materials, Swiss Federal Institute of Technology (ETH) Zurich, Switzerland. Biological surface science.

Independent work

From May 2015	Affiliate Professor, Department of Bioengineering, University of Washington - Seattle, USA.
September 2013 - September 2016	Groupleader, Platelets&Blood Compatibility Group, Institute of Functional Interfaces (IFG), Karlsruhe Institute of Technology (KIT), Germany.
January 2013 - January 2015	Professor (part-time), Faculty of Engineering, the University of the Basque Country. The position included teaching duities and conferred the rights to supervise Doctoral students.
February 2009 – February 2011	Professor (part-time), Department of Biochemistry and Molecular Biology, the University of the Basque Country. The position included teaching duities and conferred the rights to supervise Doctoral students.
September 2006 – September 2013	Groupleader, Soft Interface Biophysics group, CIC biomaGUNE, San Sebastian, Spain.

Short Stays

December 2015	Neutron Reflectometry Experiments at the Rutherford Appleton Laboratory, Didcot, UK. Proposal number RB1520054.
2015.10, 2014.12, 2013.03, 2010.09, 2009.05	Neutron Reflectometry Experiments at Institute Laue-Langevin (ILL), Grenoble, France. Proposal numbers: 8-02-751, 8-02-708, 8-02-698, 8-02-654, 8-02-560, 8-02-479.
November 2012 - December 2012	Visiting Scientist at the Department of Physical Chemistry, Clausthal Institute of Technology, Clausthal-Zellerfeld, Germany. Funded by the Alexander von Humboldt Foundation
January 2012 - July 2012	Visiting Professor at the Department of Biomedical Engineering, University of Toronto, Toronto, Canada, with the group of Prof. J. E. Davies. Platelets at implant surfaces. Platelet dysfunction in diabetes and integration of dental implants.
October 2011	Visiting Professor at the Biomedical Engineering group at the Swiss Federal Institute of Technology (Zürich, Switzerland). Funded by the Travel grant MV-2011-2-48 from the Department of Education, Universities, and Research of the Basque Government.
November 2010, August 2009	Visiting Scientist at the EMPA (Swiss Federal Laboratories for Materials Testing and Research, Dubendorf, Switzerland). ToF-SIMS experiments

Committee and Organizational Activities

Click here for the details of the conferences I have organized.

Current	2019 FEBS Advanced Lecture Course on Biological Surfaces and Interfaces: the Mechanistic View will take place June 30 - July 5, 2019, Hotel Eden Roc, Sant Feliu de Guixols, Catalonia, Spain. Marta Bally (Umeå University, Sweden), chair. Delphine Gourdon (Ottawa, Canada), Chris Lorenz (King's Kollege London, UK), co-chairs.
April 2014 - current	Member of the Editorial board of Scientific Reports.
September 2017	Organizer of the International Workshop on Blood-Biomaterial Interactions Bloodsurf2017), Clemson, SC, USA. Co-organizer: Robert Latour (Clemson University, SC, USA).
June 2017	Co-oganizer of the FEBS International Workshop on Biological Surfaces and Interfaces: Interface Dynamics, Sant Feliu, Spain. Co-organizers: Manuel Salmerón-Sánchez, University of Glasgow (UK) and Marta Bally, Chalmers University of Technology (Sweden).
2015	Guest Editor of the Special Issue of Biointerphases on Blood-Biomaterial Interactions, with Steffen Braune (Institute of Biomaterial Science and Berlin-Brandenburg Center for Regenerative Therapies, Helmholtz-Zentrum Geesthacht (HZG), Teltow, Germany).
April 2014 - April 2017	Member of Subcommittee 8 ‘Biology’ of the Institut Laue-Langevin, Grenoble, France.
2014	Oganizer of the IUVSTA International Workshop Focus on the Blood-Biomaterial Interface: Surface Analysis meets Blood Compatibility, La Villa Clythia, Fréjus, France. Co-organizers: Anouk Galtayries (ParisTech/France), Giacomo Ceccone (EU-JRC, Italy), Miguel Manso (Madrid, Spain).
2013	Oganizer of the The Iberian Membrane Biophysics Colloquium: Physics Meets Biology at the Cell Membrane, CIC biomaGUNE, San Sebastian, Spain. Co-organizer: Marisela Velez (CSIC, Institute of Catalysis, Madrid, Spain).
2010, 2012	FEBS international combined practical and lecture courses Physical Chemistry of Biointerfaces, PhysChemBio 2012 and 2010.

Mentorship, supervision

Postdoctoral Scientists
March 2010 - March 2012	Dr. Elodie Trouche (CIC biomaGUNE, Spain) Platelet Rich Plasma treatment of dental implants.
March 2011 - March 2012	Dr. Belén Sánchez Martínez de Ilárduya (CIC biomaGUNE, Spain) Growth factor release from Platelet Rich Plasma - treated dental implants.

Doctoral Students
November 2013 - December 2016	Alessia Donati (KIT, Germany) Ph.D. thesis A multilevel study of platelet activation at biomaterial surfaces: from evaluating to controlling hemocompatibility. Defended, December 2016.
December 2009 - March 2014	Swati Gupta (CIC biomaGUNE, Spain) Ph.D. thesis Selective Activation of Platelets by Surfaces and Soluble Agonists. Defended, March 2014.
May 2009 - June 2013	Ling Zhu (CIC biomaGUNE, Spain) Ph.D. thesis Investigating Lipid and Protein Organization in Cell Membrane Models. Defended, June 2013.
September 2001 - September 2005	Fernanda Rossetti (ETH Zurich, Switzerland) Ph.D. thesis Interactions of lipidic assemblies with metal oxides and brush-like polyelectrolytes. Defended, September 2005.
Master Students
August 2015 - April 2016	Eva Uhl (KIT, Germany) M.Sc. Thesis Platelet Immobilization for Single Platelet Studies.
September 2014 - August 2015	Rama Krishna Bontu (KIT and the University of Siegen, Germany) M.Sc. Thesis Analysis of blood protein adsorption and platelet activation at biomaterial surfaces.
June 2010 - February 2011	Nicole Hain (CIC biomaGUNE, Spain and Clausthal Institute of Technology, Germany) M.Sc. thesis Effect of liposome dimers on supported bilayer formation rate..
April 2009 - December 2010	Sandra Camarero Espinosa (CIC biomaGUNE and the University of the Basque Country, Spain) M.Sc. thesis Diffusion of phospholipids in solid-supported bilayers.
February 2008 - September 2008	Maitena Soubelet Fagoaga (CIC biomaGUNE and the University of the Basque Country, Spain) M.Sc. thesis Interactions between biotinylated liposomes and streptavidin 2D crystals..
January 2007 - May 2008	Edurne Teiletxea Malda (CIC biomaGUNE and the University of the Basque Country, Spain) M.Sc. thesis Interactions between lipidic vesicles and solid surfaces..
November 2000 - April 2001	Fernanda Rossetti (ETH Zurich, Switzerland) M.Sc. thesis Can Atomically Flat Titanium Oxide Surfaces be Prepared by the Template Stripping Method?.

Visiting Students and Interns
October 2015	Concepcion Molina (KIT Germany) Research assistant. Studying platelets at Biomaterial Surfaces.
June 2015	Concepcion Molina (KIT, Germany) KHYS (Karlsruhe House of Young Scientists) Aspirant Scholarship recipient. Studying platelets at Biomaterial Surfaces.
June 2015	Gennaro Ruggiero (KIT, Germany) KHYS (Karlsruhe House of Young Scientists) Aspirant Scholarship recipient. Studying platelet-SLB interactions.
November 2014 - December 2014	Tamara Spies (KIT, Germany) Undergraduate Research Assistant on the DFG project studying aminophospholipid asymmetry in membrane-mimetic solid-supported bilayers by neutron reflectometry.
March 2009 - November 2009	Nicole Hain (CIC biomaGUNE, Spain) Visiting student from the Clausthal University of Technology, Germany.
November 2008 - August 2009	Cornelis Lütgebauks (CIC biomaGUNE, Spain) Visiting student from ETH Zurich, Switzerland.
November 2008 - May 2009	Madeline Coxwell-Mathewman (CIC biomaGUNE, Spain) Visiting student from the University of York, UK.
July 2008 - August 2008	Ava Allahyar (CIC biomaGUNE, Spain) Visiting student from Chalmers Institute of Technology, Gothenburg, Sweden.
March 2008 - August 2008	Rik Matena (CIC biomaGUNE, Spain and Utrecht University, the Netherlands) ERASMUS student.
July 2007 - September 2007	Jone Muñoz Ugartemendia (CIC biomaGUNE and the University of the Basque Country, Spain) CIC biomaGUNE Summer Internship Student
October 2006 - March 2007	Tabrisur Rahman Khan (CIC biomaGUNE, Spain) Visiting student from the Royal Institute of Technology, Sweeden.

Technicians
January 2008 - September 2013	Marta Gallego-González, M.Sc. (CIC biomaGUNE, Spain)
November 2008 - January 2009	Dr. Amaia Rebollo (CIC biomaGUNE, Spain)
January 2007 - January 2008	Elena Rojas Darceles, M.Sc. (CIC biomaGUNE, Spain)

Invited Talks:


September 2017	Next-Generation Toolbox for Studying Platelet Activation: New Labels, Label-free Methods, and Single Cell Approaches. Parker H. Petit Institute for Bioengineering and Bioscience, Georgia Institute of Technology, Atlanta, GA, USA. September 2017
September 2017	Next-Generation Toolbox for Studying Platelet Activation: New Labels, Label-free Methods, and Single Cell Approaches. Page Morton Hunter Distinguished Seminar Series, Clemson Department of Bioengineering, Clemson, SC, USA. September 2017.
May 2017	Next-Generation Toolbox for Studying Platelet Activation: New Labels, Label-free Methods, and Single Cell Approaches. Department of Bioengineering, the University of Glasgow, Glasgow, UK.
March 2017	In Vitro Platelet Activation Studies: From Basic Mechanisms to Implant Integration Strategies Ben Gurion University of the Negev, Beer Sheva, Israel.
January 2017	Toolbox for Selective Platelet Activation Studies. Department of Applied Chemistry, University of Reutlingen, Reutlingen, Germany.
December 2016	Principles and Applications of Acoustic Surface Sensors. A lecture at the Biointerfaces course in the framework of the BioMaterials (BioMAT) Masters program at the Chemie-ParisTech, Paris, France.
June 2016	From blood-biomaterial interactions to hemocompatibility: where is the problem and is there a solution? i³tm (Integrated Interdisciplinary Institute of Technology for Medicine) Invited Lecture in Biointerfaces, RWTH Aachen, Germany.
June 2016	Toolbox for Studying Platelet Activation Selectivity: Models, Labels, Label-free Methods, and Single Cell Approaches. College of Chemistry, Chemical Engineering and Materials Science, Soochow University, China
April 2016	Focusing on Phosphatidyl Serine: from structural studies at the air-water interface to asymmetric bilayer model systems. Tel Aviv University Bio-Soft Matter Physics Seminar, Tel Aviv, Israel.
April 2016	Toolbox for Studying Differential Platelet Activation: Models, Labels, Label-free Methods, and Single Cell Approaches. Weizmann Institute of Science, Department of Materials and Interfaces, Rehovot, Israel.
April 2016	Focusing on Phosphatidyl Serine: from structural studies at the air-water interface to asymmetric bilayer model systems. Weizmann Institute of Science, Department of Structural Biology Seminar, Rehovot, Israel.
January 2016	Toolbox for Studying Differential Platelet Activation: Models, Labels, Label-free Methods, and Single Cell Approaches. Max Planck Institute for Intelligent Systems, Stuttgart, Germany.
September 2015	Toolbox for Studying Differential Platelet Activation: Models, Labels, Label-free Methods, and Single Cell Approaches. Molecular Engineering Seminar Series, Molecular Engineering & Sciences Institute, University of Washington, Seattle, WA, USA
March 2015	Selective Platelet Activation by Surfaces and Soluble Agonists. Leibniz-Institute for Polymer Research, Max-Bergmann-Centre for Biomaterials, Dresden, Germany.
February 2015	Hydrodynamic Effects in Laterally Heterogeneous Films Studied by QCM(-D): Application to Studying Adsorbed Liposome Deformation. Lecture and a practical demonstration at the workshop on Acoustic & Optical Systems for Studying Biomolecular Interactions. IMBB�?FORTH, Heraklion, Crete.
December 2014	Quartz Crystal Microbalance Lecture at the BioMaterials (BioMAT) Masters program at the Chemie-ParisTech, Paris, France.
November 2014	Selective Platelet Activation by Surfaces and Soluble Agonists. 33rd meeting of the Deutsche Gesellschaft für Klinische Mikrozirkulation und Hämorheologie, November 18, 2014, Schwenningen, Germany.
November 2014	Platelets and their role in reaction to biomaterials. 74th International IUVSTA workshop Focus on the Blood-Biomaterials Interface: Surface Analysis meets Blood Compatibility. November 3 – 7, Fréjus, France.
April 2014	Selective Platelet Activation by Surfaces and Soluble Agonists Institute for Biomaterials Research, Helmholtz Research Centre Geesthacht, Teltow, Germany.
January 2014	Selective Platelet Activation by Surfaces and Soluble Agonists. Institute Laue Langevin (ILL), Grenbole, France.
29�?30 August 2013	Hydrodynamic effects in laterally heterogeneous films studied by QCM(-D): Application to Studying Adsorbed Liposome Deformation Workshop on Acoustic Sensors in Analytical and Biophysical Studies, IMBB�?FORTH, Heraklion, Crete.
30 June - 05 July 2013	Form lipids to platelets: interactions between biological model systems and inorganic oxides FEBS Workshop Biological Surfaces and Interfaces Sant Feliu de Guixols, Catalonia, Spain.
May 21, 2013	Hydrodynamic effects in laterally heterogeneous films studied by QCM(-D): Studying Liposome Deformation. Soft Matter Physics and Biomembranes Workshop, Reykjavik, Iceland,
December 5, 2012	Of surfaces, ions, lipids, and platelets: Interactions of biological model systems with inorganic oxides. Seminar at the Institute for Theoretical Physics Research Seminar, Georg-August-Universität Göttingen, Germany
November 16, 2012	Of surfaces, ions, lipids, and platelets: Interactions of biological model systems with inorganic oxides. Seminar at the Department of Structure and Organization of Mater, Faculty of Physics, University of Barcelona, Spain
November 15, 2012	Of surfaces, ions, lipids, and platelets: Interactions of biological model systems with inorganic oxides. Guest lecturer at the 5th annual meeting of the Institute for Nanosciences and Nanotechnology, University of Barcelona, Barcelona, Spain
October 19, 2012	Of surfaces, ions, lipids, and platelets: Interactions of biological model systems with inorganic oxides. Seminar at the CIC energyGUNE seminar program, Vitoria, Spain,
October 10, 2012	Of surfaces, ions, lipids, and platelets: Interactions of biological model systems with inorganic oxides. Seminar at the CIC biomaGUNE seminar program, San Sebastian, Spain
April 13, 2012	Of surfaces, ions, lipids, and platelets: the role of surface ion binding in the interactions between TiO2 and biological [model] systems. Seminar at the group of the Institute of Biomaterials and Biomedical Engineering, University of Toronto, Canada
April 9, 2012	Of surfaces, ions, lipids, and platelets: the role of surface ion binding in the interactions between TiO2 and biological [model] systems. Medical Sciences Biomedical Colloquium, University of Indiana – Bloomington, USA.
September 2011	Hydrodynamic effects in laterally heterogeneous films studied by QCM(-D). QCM-D Scientific World Tour 2011, Bensheim, Germany,
April 2011	Phosphatidyl Serine Containing Liposomes on Titania: Phase Behavior, Bilayer Formation, and Lipid Asymmetry. SFB 803 Colloquium, Institut für Organische und Biomolekulare Chemie, University of Göttingen,
May 9 – 13 2011	Phosphatidyl serine containing liposomes on titania: phase behaviour, bilayer formation, and lipid asymmetry. Invited talk at the E-MRS 2011 Spring Meeting, Nice, France,
April 2011	Atomic Force Microscopy and its applications to studying transmembrane proteins. A lecture at the SICI-Advanced Course in Structural Techniques, Bilbao, Spain
April 2011	Phosphatidyl Serine Containing Liposomes on Titania: Phase Behavior, Bilayer Formation, and Lipid Asymmetry. Molecular and Nanoscale Physics Group School of Physics and Astronomy, University of Leeds, Leeds, UK.
February 2011	Interactions between Phosphatidyl Serine-containing Liposomes and Titanium Dioxide. NIST Centre for Neutron Research seminar, Gaithersburg, MD, USA
October 2010	Phosphatidyl serine containing supported lipid bilayers on titania: formation and lipid asymmetry. Franco-Iberian Nanosensor Workshop (FINW), Biarrtiz, France.
September 2010	Phosphatidyl serine containing supported lipid bilayers on titania: formation and lipid asymmetry. Department of Physics, Ludwig-Maximilians University, Munich
September 2010	Phosphatidyl serine containing supported lipid bilayers on titania: formation and lipid asymmetry. Swiss Federal Institute of Technology (Zurich), Laboratory of Biosensors and Bioelectronics,
June 2009	Studying heterogeneous soft films with quartz crystal microbalance: hearing what one can’t see and seeing what one can’t hear. Neutrons in Biology, Lund, Sweden,
May 2009	Studying heterogeneous soft films with quartz crystal microbalance: hearing what one can’t see and seeing what one can’t hear. Swiss Federal Institute of Technology (Zurich), Laboratory of Biosensors and Bioelectronics
May 2009	High-resolution imaging of biological macromolecules by atomic force microscopy: a demonstration. Veeco SPM’09 Users Workshop (Spain and Portugal), Barcelona, Spain,
May 2009	Combined Atomic Force Microscopy - Quartz Microbalance Measurements for Studying Soft, Heterogeneous Films. Veeco SPM’09 Users Workshop (Spain and Portugal), Barcelona, Spain,
December 2008	Atomic Force and Quartz Crystal Microbalance studies of soft interfaces. Department of Chemistry, University College London, London, UK
June 2008	Atomic force microscopy and quartz crystal microbalance studies of soft interfaces. Department of Chemistry, North Carolina State University, Raleigh, NC.
June 2008	Atomic force microscopy and quartz crystal microbalance studies of soft interfaces. Structural Biology and Biophysics Research Group Seminar at the School of Biological Sciences, University of Warwick, Warwick, UK
February 2008	Liposome-surface interactions. Research seminar at the group of Prof. Sarah Keller, University of Washington Dept. of Chemistry, Seattle, Washington, USA.
February 2008	Atomic force microscopy – quartz crystal microbalance system combination for investigating biomaterial-surface interactions. Seminar at the atomic force microscopy division of Agilent Technologies, Inc., Tempe, Arizona, USA.
May 2007	The touch of AFM: Feeling Molecular Structure and Dynamics. The Veeco SPM’07 Workshop, San Sebastian, Spain.
January 2007	Interactions of phospholipid vesicles with titanium dioxide: the role of Ca2+. The joint Biophysics centre, University of the Basque Country, Leioa, Spain.
January 2006	Interactions of phospholipid vesicles with titanium dioxide. Department of Biochemistry, University of Oxford, Oxford, , UK
August 2005	Crystallisation of Soluble and Transmembrane Proteins Studied by Atomic Force Microscopy in Solution. Department of Materials, Swiss Federal Institute of Technology (ETH) Zurich. August 2005, Zürich, Switzerland.
June 2005	Interactions of phospholipid vesicles with titanium dioxide. Institute for Physical Chemistry, Department of Biophysical Chemistry, University of Heidelberg, Germany.
April 2005	Crystallization of Soluble and Transmembrane Proteins Studied by Atomic Force Microscopy in Solution. Department of Biological Sciences, University of Warwick Department of Biology, Warwick, UK.
March 2005	Formation of Supported Phospholipid Bilayers on Titanium Dioxide. Department of Chemistry, Imperial College London, London, UK.
January 2005	Crystallisation of Soluble and Transmembrane Proteins Studied by Atomic Force Microscopy in Solution. Institute of Physical Chemistry, Technical University Clausthal, Clausthal-Zellerfeld, Germany.
July 2004	Formation of Supported Phospholipid Bilayers on titanium Dioxide. University of Leeds, Department of Biochemistry and Microbiology, Leeds, UK.
April 2004	Supported lipidic systems. University of Houston, Houston, TX, USA
May 2003	Growth of Insulin Crystals Monitored by Atomic Force Microscopy. University of Bordeaux - 1, Bordeaux, France.
May 2003	Viscoelastic Properties of Supported Vesicular Layers on Titanium Dioxide. Swiss Federal Institute of Technology - Lausanne (EPFL), Lausanne, Switzerland.
October 2002	The "Touch" of AFM: Studying Molecular Structure and Dynamics. The OChEGS Symposium, October 2002, University of Houston, Houston, Texas.
April 2002	Tailoring adsorption of proteins, Directing attachment of cells, Studying the behaviour of vesicles on surfaces. Department of Chemistry and Biochemistry, University of South Carolina at Columbia, Columbia, South Carolina.
March 2002	Behaviour of Phospholipid Vesicles on Various Surfaces. Sandia National Laboratories, March 2002, Livermore, California.
March 2001	Growth of Protein Two-dimensional Crystals on Supported Phosholipid Bilayers Investigated by Atomic Force Microscopy: Transition Between Crystal Forms. Dental Material and Biomaterial Section of the Department of Oral and Dental Science, Faculty of Medicine, University of Bristol. Bristol, UK
February 2001	Growth of Protein Two-dimensional Crystals on supported Phosholipid Bilayers Investigated by Atomic Force Microscopy. Special Seminar at the group of Prof. G. M. Whitesides, Department of Chemistry, Harvard University, Boston, MA.
April 2000	Formation of Supported Phospholipid Bilayers (SPBs) and Growth of Protein Two-Dimensional Crystals On SPBs Investigated By Atomic Force Microscopy. University of Washington Centre For Nanotechnology Seminar. Seattle, Washington
April 2000	Formation of Supported Phospholipid Bilayers (SPBs) and Growth of Protein Two-Dimensional Crystals On SPBs Investigated By Atomic Force Microscopy. University of California, Santa Barbara Department of Chemistry Seminar. April 2000, Santa Barbara, California.
March 2000	Formation of Supported Phospholipid Bilayers (SPBs) and Growth of Protein Two-Dimensional Crystals On SPBs Investigated By Atomic Force Microscopy. Carnegie Mellon University Colloids, Polymers and Surfaces Program Seminar. Pittsburgh, PA.
March 2000	Formation of Supported Phospholipid Bilayers and Growth of Protein Two-dimensional Crystals on SPBs Investigated by AFM. Department of Materials, Swiss Federal Institute of Technology (ETH) Zurich. Zurich, Switzerland